"The great saphenous vein is the major superficial vein of the medial leg and thigh. It is the longest vein in the human body, extending from the top of the foot to the upper thigh and groin. The great saphenous vein plays an important role in returning blood from the superficial tissues of the leg to the heart and is also used in several medical procedures due to its size and superficial location.
The great saphenous vein is a superficial vein that runs through the subcutaneous tissue layer deep to the dermis and superficial to the skeletal muscles of the foot and leg.
It begins at the dorsal venous arch of the foot, a major superficial vein that drains blood from the toes and back of the foot. From the dorsal venous arch, the great saphenous vein passes anterior to the medial malleolus of the ankle and enters the medial side of the leg. As it ascends through the leg, it merges with many superficial veins of the leg before passing over the medial epicondyle of the femur at the knee and entering the thigh. Continuing through the thigh, the great saphenous vein turns anteriorly while merging with several more superficial veins. At the top of the thigh, it passes through the saphenous opening of the fascia lata and enters the deeper tissues of the upper thigh before merging into the femoral vein."
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